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Molecular Printboards on Silicon Oxide: Lithographic Patterning of Cyclodextrin Monolayers with Multivalent, Fluorescent Guest Molecules
Author(s) -
Mulder Alart,
Onclin Steffen,
Péter Mária,
Hoogenboom Jacob P.,
Beijleveld Hans,
ter Maat Jurjen,
GarcíaParajó María F.,
Ravoo Bart Jan,
Huskens Jurriaan,
van Hulst Niek F.,
Reinhoudt David N.
Publication year - 2005
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200400063
Subject(s) - microcontact printing , monolayer , dip pen nanolithography , materials science , nanotechnology , nanolithography , supramolecular chemistry , fluorescence , molecule , self assembly , ethylene glycol , self assembled monolayer , chemical engineering , chemistry , organic chemistry , fabrication , medicine , alternative medicine , physics , pathology , quantum mechanics , engineering
Three compounds bearing multiple adamantyl guest moieties and a fluorescent dye have been synthesized for the supramolecular patterning of β‐cyclodextrin (CD) host monolayers on silicon oxide using microcontact printing and dip‐pen nanolithography. Patterns created on monolayers on glass were viewed by laser scanning confocal microscopy. Semi‐quantitative analysis of the patterns showed that with microcontact printing approximately a single monolayer of guest molecules is transferred. Exposure to different rinsing procedures showed the stability of the patterns to be governed by specific supramolecular multivalent interactions. Patterns of the guest molecules created at CD monolayers were stable towards thorough rinsing with water, whereas similar patterns created on poly(ethylene glycol) (PEG) reference monolayers were instantly removed. The patterns on CD monolayers displayed long‐term stability when stored under N 2 , whereas patterns at PEG monolayers faded within a few weeks due to the diffusion of fluorescent molecules across the surface. Assemblies at CD monolayers could be mostly removed by rinsing with a concentrated CD solution, demonstrating the reversibility of the methodology. Patterns consisting of different guest molecules were produced by microcontact printing of one guest molecule and specific adsorption of a second guest molecule from solution to non‐contacted areas, giving well‐defined alternating assemblies. Fluorescent features of sub‐micrometer dimensions were written using supramolecular dip‐pen nanolithography.