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Optical and Electrochemical Detection of NADH and of NAD + ‐Dependent Biocatalyzed Processes by the Catalytic Deposition of Copper on Gold Nanoparticles
Author(s) -
Shlyahovsky Bella,
Katz Eugenii,
Xiao Yi,
Pavlov Valeri,
Willner Itamar
Publication year - 2005
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200400057
Subject(s) - nicotinamide adenine dinucleotide , nad+ kinase , electrochemistry , catalysis , nanoparticle , cofactor , copper , materials science , biocatalysis , nanotechnology , chemistry , combinatorial chemistry , nuclear chemistry , electrode , enzyme , organic chemistry , metallurgy
Au/Cu core/shell nanoparticle assemblies on modified quartz or ITO slides are achieved through a biochemical reduction process, in which 1,4‐dihydro‐β‐nicotinamide adenine dinucleotide (NADH) performs the Au‐catalyzed reduction of Cu 2+ ions (see scheme). Such assemblies are ideal for the optical or electrochemical detection of NADH and NAD + ‐dependent biocatalytic processes, such as the analysis of ethanol.