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2,2,6,6‐Tetramethylpiperidinyloxyl (TEMPO) Radical Mediated Electro‐Oxidation Reactions: A Review
Author(s) -
Prakash Nishitha,
Rajeev Rijo,
John Anjali,
Vijayan Ajesh,
George Louis,
Varghese Anitha
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202102346
Subject(s) - oxidizing agent , chemistry , reagent , reactivity (psychology) , alcohol oxidation , cyclic voltammetry , combinatorial chemistry , yield (engineering) , electrochemistry , organic chemistry , green chemistry , radical ion , electrocatalyst , redox , catalysis , reaction mechanism , materials science , medicine , alternative medicine , electrode , pathology , metallurgy , ion
Over the last few decades, the interest in green and sustainable chemistry has led to the development of different synthetic methodologies which utilize clean reagents. In that direction, the electro‐oxidation reactions are considered as one of the most interesting and promising methods. This is predominantly due to their environmentally benign nature, as oxidation can be achieved without the need for commonly used oxidizing agents. 2,2,6,6‐Tetramethylpiperidinyloxyl radical commonly known as TEMPO is a stable aminoxyl radical utilized for the oxidation of various classes of alcohols to carbonyl compounds by using cyclic voltammetry. The present review focuses on the various electrochemical reactions utilizing TEMPO as a mediator such as the oxidative conversion of alcohols, carbohydrates, amines, sulphur‐containing compounds, and alkenes in both laboratory as well as industrial scales and covers literature from 1950 till present date. The properties, reactivity, and yield percentages of these reactions would provide a basis for better electrocatalyst design in future studies involving TEMPO and its derivatives as mediators.