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Triethanolamine‐Mediated Magnetically Separable Fe 3 O 4 −Pd Nanoparticles Catalyzed Heck Reaction under Ligand‐Free Conditions
Author(s) -
Kumar Pal Chandan,
Kumar Jena Ashis,
Das Dibya,
Sahu Swagatika,
Kumar Singh Rajesh
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202102339
Subject(s) - triethanolamine , heck reaction , catalysis , aryl , ligand (biochemistry) , chemistry , styrene , nanoparticle , coupling reaction , medicinal chemistry , combinatorial chemistry , polymer chemistry , palladium , organic chemistry , materials science , nanotechnology , copolymer , analytical chemistry (journal) , biochemistry , alkyl , receptor , polymer
The Fe 3 O 4 −Pd nanoparticles catalyzed Heck coupling reaction in triethanolamine was performed for the first time in absence of any external ligand. The Fe 3 O 4 −Pd/triethanolamine/100 °C catalytic system was found to be highly active in achieving good to excellent yields of the desired ( E )‐alkenes. Both acrylates and styrene derivatives were successfully coupled with electron‐rich and electron‐deficient aryl iodides. The scope of the reaction was also expanded to less reactive aryl bromides and aryl chlorides albeit in lower yields. A number of functional groups were well tolerated. More significantly the catalyst showed good recyclability and can be reused up to four consecutive cycles without any decrease in catalytic activity.