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Palladium‐Catalyzed Aryl‐Carbamoylation of Alkene‐Tethered Carbamoyl Chlorides: Access to Diverse Aryl‐Functionalized Oxindoles
Author(s) -
Chen Chen,
Liu Liying,
Sun Wan,
Zhu Bolin
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202101985
Subject(s) - aryl , alkene , palladium , catalysis , cascade , chemistry , combinatorial chemistry , intermolecular force , organic chemistry , molecule , alkyl , chromatography
Utilizing a palladium‐catalyzed cascade strategy, we have developed an intermolecular aryl‐carbamoylation of unactivated alkenes under mild conditions, allowing for facile access to diverse aryl‐functionalized oxindoles from alkene‐tethered carbamoyl chlorides in moderate to good yields.