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I 2 ‐Catalyzed Tandem Annulation of Ketene Dithioacetals with Sulfonyl Hydrazides for the Synthesis of N ‐Aminosulfonamides
Author(s) -
Chen Tianpeng,
Shen Jing,
Wang Mingliang,
Xu Xiaoliang,
Cheng Dongping
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202101554
Subject(s) - sulfonyl , annulation , ketene , chemistry , tandem , catalysis , pyrazole , aryl , alkyl , medicinal chemistry , iodine , organic chemistry , combinatorial chemistry , materials science , composite material
An iodine‐catalyzed tandem annulation of ketene dithioacetals with sulfonyl hydrazides is established, which gives the N ‐aminosulfonamides with pyrazole side chain in moderate yields. A series of aryl, heteroaryl, and alkyl substituted sulfonyl hydrazides are compatible with this reaction.