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Synthesis and Biological Properties of Coumarin Derivatives. A Review
Author(s) -
Bouhaoui Abderrazzak,
Eddahmi Mohammed,
Dib Mustapha,
Khouili Mostafa,
Aires Alfredo,
Catto Marco,
Bouissane Latifa
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202101346
Subject(s) - coumarin , combinatorial chemistry , chemistry , reactivity (psychology) , catalysis , biological activity , organic chemistry , biochemistry , in vitro , medicine , alternative medicine , pathology
Coumarin and its derivatives are widely used as scaffolds in the synthesis of new heterocyclic systems. This review focuses on current developments in the synthesis of heterocyclic coumarin compounds. Numerous approaches especially involving nanoparticle catalysts have been developed to get new bioactive coumarin derivatives endowed with pharmacological and biological activities. The present work describes the reactivity and the new strategies using various catalysts for the synthesis of coumarin and its derivatives reported in the literature and their biological properties.