Premium
Task‐Specific Deep Eutectic Solvent for Selective Oxidation of Aromatic Methyl to Aldehyde
Author(s) -
Bhise Rupali S.,
Patel Khushbu P.,
Ghorpade Prashant V.,
Shankarling Ganapati S.
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202101109
Subject(s) - deep eutectic solvent , choline chloride , aldehyde , yield (engineering) , catalysis , chemistry , solvent , eutectic system , organic chemistry , combinatorial chemistry , materials science , alloy , metallurgy
Biodegradable and economically viable choline chloride‐FeCl 2. H 2 O deep eutectic solvent (DES), was synthesized and successfully utilized as a catalyst and reaction medium for the selective oxidation of aromatic methyl groups to aldehydes. To demonstrate the synthetic potential of this protocol, the reaction was scaled up to the gram scale. The DES could be reused up to four times without considerable effect on the yield of the reaction. The key features of the protocol that qualify the process as green include the ambient reaction temperatures, easy isolation of the products, higher yields, recyclability of the catalyst, and reactions without the use of conventional organic solvents.