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Microwave‐Assisted Green Synthesis of 2,3‐Dihydroquinazolinones under Base‐ and Catalyst‐Free conditions
Author(s) -
Kerdphon Sutthichat,
Jongcharoenkamol Jira,
Chatwichien Jaruwan,
Singh Thishana,
Channei Duangdao,
Choommongkol Vachira,
Rithchumpon Puracheth,
Meepowpan Puttinan
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202101063
Subject(s) - catalysis , base (topology) , microwave irradiation , aqueous solution , microwave , chemistry , reaction conditions , green chemistry , organic chemistry , nuclear chemistry , reaction mechanism , mathematics , computer science , mathematical analysis , telecommunications
A facile and green one‐pot synthesis of 2,3‐dihydroquinazolinones, using microwave irradiation, has been developed. Dihydroquinazolinones were synthesized from 2‐aminobenzamide derivatives and various aldehydes in aqueous solution under base and catalyst free reaction conditions. The desired products, from aliphatic and aromatic aldehydes substrates, were obtained in 5 minutes with up to 99 % isolated yields.