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Silver‐Catalyzed Cross Dehydrogenative Coupling between Heteroarenes and Cyclic Ethers under Mild Conditions
Author(s) -
Zhou Zhong,
Wu Yunli,
Yang Peng,
Deng Shijun,
Zhang Qian,
Li Dong
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202100339
Subject(s) - catalysis , coupling (piping) , chemistry , materials science , polymer chemistry , combinatorial chemistry , organic chemistry , composite material
A new strategy for the straightforward alkylation of heteroarenes under mild conditions was developed. It employed silver catalyst for the cross dehydrogenative coupling between heteroarenes and cyclic ethers to construct a new C(sp 2 )−C(sp 3 ) bond. This reaction was carried out in water under room temperature and applicable to various heteroarenes such as pyridines, quinolines and isoquinolines derivatives with good functional group compatibility.