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One‐pot Suzuki Coupling‐Knoevenagel Condensation Tandem Reaction Catalyzed by a Recyclable Magnetic Bifunctional Catalyst
Author(s) -
Yuan Xiaofeng,
Wang Jinyuan,
Wan Zijuan,
Zhang Qiang,
Luo Jun
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202004158
Subject(s) - knoevenagel condensation , bifunctional , catalysis , tandem , suzuki reaction , chemistry , phosphine , coupling reaction , bifunctional catalyst , organic chemistry , cascade reaction , polymer chemistry , materials science , palladium , composite material
A novel magnetic nanoparticle‐supported bifunctional catalyst NH−Pd(0)@MNP was prepared and its activity was evaluated in one‐pot Suzuki coupling‐Knoevenagel condensation tandem reaction. A series of biaryl derivatives were synthesized via sequential Suzuki coupling‐Knoevenagel condensation in ethanol/water medium under phosphine‐free conditions. Meanwhile, the catalyst could be easily separated by an external magnetic field, and could be reused several times without remarkable loss of catalytic activity.