Premium
Design, Synthesis and Biological Evaluation of Stilbene Derivatives Containing a 1,3‐Benzodioxole Moiety
Author(s) -
Song Di,
Cao Xiufang,
Huang Wenbo,
Ke Shaoyong
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202003860
Subject(s) - moiety , chemistry , biological activity , combinatorial chemistry , broad spectrum , stereochemistry , proton nmr , organic chemistry , in vitro , biochemistry
Stilbene is an important class of biologically active metabolites with diarylethene scaffold, and which have a broad range of biological activities as the lead for drug discovery. In this study, a novel series of stilbene derivatives bearing 1,3‐benzodioxole moiety was designed and synthesized via a convenient method with good to excellent yields, and their structures were characterized by 1 H NMR, 13 C NMR, ESI‐MS spectrum. These newly prepared compounds were evaluated for their potential biological activities including fungicidal, insecticidal, and cytotoxic activities.