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Recent Advances of Indium(III) Chloride Catalyzed Reactions in Organic Synthesis
Author(s) -
Datta Mrityunjoy
Publication year - 2021
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202003828
Subject(s) - organic synthesis , catalysis , indium , chemistry , heteroatom , lewis acids and bases , nucleophile , chloride , lewis acid catalysis , organic chemistry , combinatorial chemistry , ring (chemistry)
This review summarizes recent advances of indium trichloride catalyzed synthesis of different organic compounds. It is obvious that InCl 3 co‐ordinates with C−C and/or C‐heteroatom multiple bonds and thereby makes them very prone to nucleophilic attack to form a new bond. This Lewis acid catalyst also activates oxiranes to produce aldehydes. Multicomponent synthesis including C−C bond formation reaction and construction of N, O and S‐containing heterocycles are discussed in organic solvents as well as in water. This article highlights recent developments and application of indium(III) chloride as a catalyst in organic synthesis from 2015 to 2020. The mechanism of few important reactions is discussed in detail which will be very useful for the readers.