Premium
Template‐Directed Synthesis of Two Dinuclear Ni(II) Complexes together with Their Interconversion, Crystal Structures and DNA‐Binding Studies
Author(s) -
Wang Yang,
Wu Zhongyuan,
Liu Yuxiu,
Liu Yulan,
Qiu Yinsheng,
Yan Juntao,
Cheng Xianzhong,
Zhou Guoqing
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202003007
Subject(s) - chemistry , methylene , benzaldehyde , crystallography , single crystal , square pyramidal molecular geometry , crystal structure , ion , infrared spectroscopy , mass spectrum , stereochemistry , molar conductivity , spectroscopy , electrochemistry , elemental analysis , medicinal chemistry , inorganic chemistry , organic chemistry , catalysis , electrode , physics , quantum mechanics
Dinuclear Ni(II) macrocyclic complex A ([Ni 2 L 1 OAc]ClO 4 ⋅CH 3 OH⋅H 2 O) and dinuclear Ni(II) acyclic complex B ([Ni 2 L 2 ](ClO 4 ) 2 ) were synthesized by condensation between H 2 L (3,3′‐(ethane‐1,2‐diylbis(benzylazanediyl))bis(methylene)bis(2‐hydroxy‐5‐methyl‐benzaldehyde)) and different molar equivalent 1,3‐propanediamine in the presence of Ni(II) ions. The structures of complexes were characterized by IR spectroscopy, elemental analysis, electrospray mass spectra and X‐ray single crystal diffraction. In complex A , the Ni(II)‐Ni(II) distance was 2.9413(7) Å, bridged by two phenolic oxygens and an acetate anion, while in complex B , it was 3.0540(1) Å, only bridged by two phenolic oxygens. The calf thymus DNA (CT‐DNA) binding ability was studied through spectroscopic and electrochemical methods, the corresponding binding constant for complexes A and B were 6.45×10 4 M −1 and 8.65×10 4 M −1 , respectively. The MS revealed that B can transform to A by adding more H 2 L, and A cannot transform to B in the presence of excess 1,3‐propanediamine.