Cyclopentene Synthesis by a Catalytic [3+2] Annulation of Donor‐Acceptor Cyclopropanes with Polarized Alkenes | Zendy

Xu Cong | Zendy; Wei Na | Zendy; Zhu Dongsheng | Zendy; Wang Mang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Cyclopentene Synthesis by a Catalytic [3+2] Annulation of Donor‐Acceptor Cyclopropanes with Polarized Alkenes

Author(s) -

Xu Cong,

Wei Na,

Zhu Dongsheng,

Wang Mang

Publication year - 2020

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.202002967

Subject(s) - annulation , cyclopentene , chemistry , catalysis , ketene , intramolecular force , lewis acids and bases , acceptor , medicinal chemistry , ring (chemistry) , photochemistry , stereochemistry , organic chemistry , physics , condensed matter physics

[3+2] Annulation of donor‐acceptor cyclopropanes with alkynes represents an efficient route to cyclopentenes. Here, we describe a new cyclopentene synthesis via Lewis acid‐catalyzed ring‐opening addition and intramolecular S N V reaction of donor‐acceptor cyclopropanes with alkenes. The reaction is carried out under the catalysis of Sc(OTf) 3 by using polarized alkenes, namely α‐oxo ketene dithioacetals, as 2 C partners.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research