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Ultrasonic‐Assisted Hypervalent Iodine‐Catalyzed Cyclization of ( E )‐2‐Hydroxystilbenes to Benzofurans Using Iodobenzene as Pre‐catalyst
Author(s) -
Mangaonkar Saeesh R.,
Shetgaonkar Samata E.,
Vernekar Amit A.,
Singh Fateh V.
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202002860
Subject(s) - hypervalent molecule , iodobenzene , catalysis , iodine , chemistry , organic chemistry , nuclear chemistry , medicinal chemistry
Abstract A rapid, and metal‐free approach for the synthesis of functionalized benzofurans 10 is illustrated by PhI 9 catalyzed cyclization of 2‐hydroxystilbenes 8 . The 2‐hydroxystilbenes 8 were cyclized using 10 mol % PhI as a precatalyst, 2.0 equiv. of m ‐CPBA as an oxidant and 2.4 equiv. of TFA as an additive at room temperature under ultrasonic irradiation condition. The functionalized benzofurans 10 were gained in good to excellent yields with shorter reaction times.