Premium
Construction of Unique Polycyclic 3, 4‐Fused Indoles via Rhodium(III)‐Catalyzed Domino Annulations **
Author(s) -
Raji Reddy Chada,
Sathish Puppala,
Mallesh Kathe,
Lakshmi Prapurna Y.
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202002689
Subject(s) - annulation , domino , rhodium , indole test , alkyne , catalysis , chemistry , combinatorial chemistry , stereochemistry , organic chemistry
A novel and efficient domino annulation for the construction of unrevealed polycyclic 3, 4‐fused indoles involving rhodium(III)‐catalyzed alkyne insertion followed by aza ‐Michael addition is presented. A variety of N ‐(pivaloyloxy)arylamides and N ‐(pivaloyloxy)‐1 H ‐indole‐1‐carboxamides were utilized in this annulation with 4‐alkynyl‐3‐alkenyl indoles.