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Catalyst‐Free Synthesis of α‐Diazoketones in Water by Microwave Promoted Enaminone C=C Double Bond Cleavage
Author(s) -
Gan Lu,
Wei Li,
Wan JiePing
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202002247
Subject(s) - sulfonyl , catalysis , chemistry , cycloaddition , microwave irradiation , tandem , decomposition , azide , microwave , ring (chemistry) , photochemistry , combinatorial chemistry , organic chemistry , materials science , alkyl , physics , quantum mechanics , composite material
The reactions of enaminones with methyl sulfonyl azide providing α‐diazoketones have been realized in pure water by means of microwave irradiation. Besides the green medium and energy source, the reactions benefit additional advantages of sustainability from the totally catalyst‐ and additive‐free conditions. More significantly, the synthesis remarks the first successful application of the featured tandem [3+2] cycloaddition and subsequent ring decomposition of the in situ generated 1,2,3‐triazoline intermediate from enaminones and sulfonyl azide in the synthesis of α‐diazoketones.