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Palladium‐Catalyzed One‐Pot Coupling / Cyclization through Mo(CO) 6 as the Carbon Monoxide Donor: Synthesis of Quinazolinones
Author(s) -
Tao ShouWei,
Liu RuiQing,
Zhou JingYa,
Zhu YongMing
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202002111
Subject(s) - quinazolinone , palladium , carbon monoxide , aryl , catalysis , substrate (aquarium) , functional group , coupling (piping) , chemistry , combinatorial chemistry , coupling reaction , organic chemistry , materials science , metallurgy , alkyl , oceanography , polymer , geology
An efficient and rapid one‐pot synthesis of quinazolinone via a three‐component carbonylative coupling of 2‐aminobenzamide or 2‐aminobenzonitrile, Mo(CO) 6 and aryl bromides has been developed recently. This method provide a new way to synthesize quinazolinone which has a wide substrate scope, good functional group tolerance and mild reaction condition.