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Hypervalent Iodine Reagent‐Mediated Selective Vinyl C−H Amidation of 4‐Alkoxystyrenes with Diarylsulfonimides for Preparation of Enamides
Author(s) -
Wang Xia,
Liu Hao,
Xiang Dehu,
Zhang Qian,
Li Dong
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202001689
Subject(s) - hypervalent molecule , reagent , iodine , chemistry , regioselectivity , aromatization , organic chemistry , combinatorial chemistry , catalysis
A selective vinyl C−H amidation of 4‐alkoxystyrenes with diarylsulfonimides has been developed for preparation of enamides. The reaction was mediated by a hypervalent iodine reagent through a radical dearomatization/aromatization process. It proceeded under metal‐free, mild and neutral conditions with good air and moisture tolerance, providing the highly regioselective enamide products in moderate to good yields.