Premium
Review of Zinc(II) Scaffolds: Efficient Role in Gene Delivery
Author(s) -
Muripiti Venkanna,
Gondru Ramesh,
Patri Srilakshmi V.
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202001557
Subject(s) - gene delivery , nanotechnology , genetic enhancement , cationic polymerization , robustness (evolution) , zinc , delivery system , gene , computational biology , viral vector , bioinformatics , biology , chemistry , materials science , genetics , recombinant dna , pharmacology , organic chemistry
Over the past two decades, enormous research has been focused on cationic non‐viral vectors because of their advantages like flexible properties, easy synthesis, robustness, etc. It was also proved that, because of their efficient gene delivery properties, Zinc cationic lipids have received great attention as promising non‐viral gene‐delivery systems. Herewith, the review mainly aimed at the most recent scientific advances of Zinc‐metal coordinative non‐viral gene‐delivery systems. The major progress in the fields of gene‐delivery as well as tissue engineering applications are summarized in the current review.