Premium
Copper‐Catalyzed sp 3 ‐Carbon Radical/Halogen Radical Cross Coupling: Selective Halogenation of 1,3‐Dicarbonyl Compounds
Author(s) -
Lv ShuaiShuai,
Yan XuPing,
Li ChengKun,
Zhou ShaoFang,
Shoberu Adedamola,
Zou JianPing
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202000947
Subject(s) - halogenation , halogen , halide , chemistry , catalysis , copper , medicinal chemistry , coupling (piping) , carbon fibers , halocarbon , organic chemistry , materials science , alkyl , composite number , metallurgy , composite material
A new copper‐catalyzed sp 3 ‐carbon radical/halogen radical cross‐coupling strategy for the formation of C(sp 3 )‐X bond is described. This provides a general method for synthesis of α ‐halogenated and α , α ‐dihalogenated‐1,3‐dicarbonyl compounds using sodium halides as halogen source under mild conditions.