Iodine‐Mediated Oxidative Annulation by C–C Cleavage: A Domino Synthetic Approach to Quinazolinones and Benzo[4,5]imidazo[1,2‐ c ]quinazolines | Zendy

Donthiboina Kavitha | Zendy; Mani Geeta Sai | Zendy; Shankaraiah Nagula | Zendy; Kamal Ahmed | Zendy

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Iodine‐Mediated Oxidative Annulation by C–C Cleavage: A Domino Synthetic Approach to Quinazolinones and Benzo[4,5]imidazo[1,2‐ c ]quinazolines

Author(s) -

Donthiboina Kavitha,

Mani Geeta Sai,

Shankaraiah Nagula,

Kamal Ahmed

Publication year - 2020

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.202000682

Subject(s) - annulation , domino , chemistry , iodine , oxidative cleavage , combinatorial chemistry , cleavage (geology) , oxidative phosphorylation , bond cleavage , peroxide , stereochemistry , organic chemistry , catalysis , biochemistry , materials science , fracture (geology) , composite material

A facile iodine‐mediated unprecedented C–C cleavage by employing CuI has been established towards the synthesis of quinazolin‐4(3 H )‐ones and benzo[4,5]imidazo[1,2‐ c ]quinazolines. This protocol involves peroxide free synthetic approach for the stable C–C bond cleavage followed by oxidative annulation to develop a library of fused N ‐heterocyclic molecules.

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