A Selective and Reversible Fluorescent Probe for Zn 2+  Detection in Living Cells | Zendy

Chen Xin | Zendy; Ma Yufan | Zendy; Zhang Yuanyuan | Zendy; Chen Qing | Zendy; Wang Hongmei | Zendy; Wang Zhuo | Zendy

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A Selective and Reversible Fluorescent Probe for Zn 2+ Detection in Living Cells

Author(s) -

Chen Xin,

Ma Yufan,

Zhang Yuanyuan,

Chen Qing,

Wang Hongmei,

Wang Zhuo

Publication year - 2020

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.202000662

Subject(s) - fluorescence , detection limit , metal ions in aqueous solution , chemistry , biocompatibility , selectivity , aqueous solution , ion , zinc , metal , interference (communication) , analytical chemistry (journal) , inorganic chemistry , chromatography , biochemistry , optics , catalysis , physics , channel (broadcasting) , electrical engineering , organic chemistry , engineering

A newly 8‐aminoquioline based fluorescent probe ( NQA ) was designed and synthesized as a good turn‐on fluorescence sensor to reversibly detect Zn 2+ . The probe can detect Zn 2+ in an aqueous solution with good selectivity without interference from other metal ions (Cd 2+ in particular). And the limit of detection was calculated to be 2.15×10 −9 M. The probe can efficiently monitor the change of concentration of Zn 2+ in a broad pH range from 4.0 to 11.0. NQA can detection of Zn 2+ reversibly based on the coordination interaction. NQA is biocompatibility and can be used to monitor the concentration of Zn 2+ in living cells without the interference from other similar cations, especially Cd 2+ .

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