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Synthesis of 2‐Arylbenzoselenazoles from Se‐mediated Redox Condensation of 2‐Chloronitrobenzene and Arylmethyl Chloride
Author(s) -
Gan Haifeng,
Cao Mengru,
Wu Hongli
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202000642
Subject(s) - redox , selenium , chemistry , condensation , chloride , metal , condensation reaction , gram , inorganic chemistry , polymer chemistry , organic chemistry , catalysis , bacteria , physics , genetics , biology , thermodynamics
A selenium‐mediated redox condensation of 2‐chloronitrobenzene and arylmethyl chloride to obtain 2‐arylbenzoselenazoles has been realized under metal‐free condition. The reactions proceeded in moderate‐to‐good yields with good functional compatibility and gram‐scale achievement. Primarily mechanistic investigation suggested that key intermediate Bn(Se)nBn II , was first isolated and confirmed by NMR.