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I 2 ‐Initiated Reduction of α‐Ketoesters with a Hydrosilane
Author(s) -
Jiang Jin,
Xiao Lili
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.202000234
Subject(s) - iodine , reduction (mathematics) , chemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , mathematics , geometry
Molecular iodine is widely used because of its environmental friendliness and easy operation. In this work, a novel reduction system involved molecular iodine and a hydrosilane for the reduction of α‐ketoesters to the corresponding α‐hydroxy esters has been developed. And the I 2 ‐HSiEt 3 system showed its mild reaction conditions and high efficiency.
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