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A Facile L‐Proline Catalyzed One‐Pot Synthesis of Xanthene and Acridine Based Quinolones via Knoevenagel Condensation Reaction
Author(s) -
Reddy Manne Madhava,
Sivaramakrishna Akella
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201904921
Subject(s) - xanthene , dimedone , knoevenagel condensation , chemistry , acridine , ammonium acetate , catalysis , proline , organic chemistry , condensation reaction , combinatorial chemistry , amino acid , biochemistry , high performance liquid chromatography
Abstract A highly efficient, three‐component one‐pot and L‐proline catalyzed Knoevenagel condensation reaction of substituted‐2‐phenoxyquinoline‐3‐carbaldehyde, 1,3‐cyclohexanedione/dimedone or ammonium acetate is described. These reactions afford unexpected products of xanthene and acridine based quinolones in ethanol with good yields. All these isolated products are characterised by spectroscopic and analytical data.