A BODIPY‐Hemicyanine‐Based Water‐Soluble Dual‐Color Fluorescence Probe for Colorimetric Monitoring of Intracellular Endogenous Sulfur Dioxide and Bioimaging Applications | Zendy

Liu Ying | Zendy; Wu YongXiang | Zendy; Zhang Dailiang | Zendy; Xi Yang | Zendy; Yu Shengrong | Zendy; Zhong Hongmei | Zendy; He Kangdi | Zendy; Li Dian | Zendy; Wei WenTing | Zendy; Cao Yuting | Zendy; Gan Ning | Zendy

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A BODIPY‐Hemicyanine‐Based Water‐Soluble Dual‐Color Fluorescence Probe for Colorimetric Monitoring of Intracellular Endogenous Sulfur Dioxide and Bioimaging Applications

Author(s) -

Liu Ying,

Wu YongXiang,

Zhang Dailiang,

Xi Yang,

Yu Shengrong,

Zhong Hongmei,

He Kangdi,

Li Dian,

Wei WenTing,

Cao Yuting,

Gan Ning

Publication year - 2020

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201904900

Subject(s) - bodipy , fluorescence , chemistry , endogeny , intracellular , nucleophile , aldehyde , photochemistry , sulfur dioxide , biophysics , biochemistry , organic chemistry , catalysis , biology , physics , quantum mechanics

We conjugated aldehyde‐BODIPY with the water‐soluble iodopropionic‐acid‐hemicyanine to develop a new dual‐color fluorescence probe (BHC) for selective and sensitive monitoring of endogenous SO 2 for the first time. Through excellent water solubility and the unique nucleophilic addition reaction, BHC has a higher selectivity for the colorimetric monitoring of SO 2 than other related substances. The resulting probe BHC has red emission, and can be converted to green emission after reacting with SO 2 . Then the dual‐color fluorescence probe was further applied to image intracellular endogenous generated SO 3 2− /HSO 3 − by the metabolism of living cells with satisfactory results. This strategy provides a new tool for revealing the metabolism of SO 3 2− /HSO 3 − and quantifying their distribution in living cells.

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