Premium
Efficient and Uncatalyzed Synthesis of Highly Functionalized New Symmetrical Indeno[1,2‐ b ]pyrroles via a One‐Pot Four‐Component Reaction
Author(s) -
Rezvanian Atieh,
Mahmoodi Fahame,
Zadsirjan Vahideh,
Salimi Mehri,
Heravi Majid M.
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201904860
Subject(s) - ninhydrin , diketene , catalysis , component (thermodynamics) , reaction conditions , chemistry , pyrrole , functional group , diamine , combinatorial chemistry , organic chemistry , polymer chemistry , biochemistry , physics , polymer , amino acid , thermodynamics
A facile, efficient and un‐catalyzed approach for the synthesis of new symmetrical highly‐ substituted indeno [1,2‐ b ]pyrrole derivatives through four‐component reaction, involving, primary amines, diamine, diketene, and ninhydrin in CH 2 Cl 2 at ambient temperature is reported. This approach enjoys merits such as being done in the absence of catalyst at ambient temperature, giving good to excellent yields, completed in short reaction times, and showing a wide functional group tolerance.