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Knoevenagel Condensation and Michael Addition in Bio‐Renewable Deep Eutectic Solvent: Facile Synthesis of a Library of Bis‐enol Derivatives
Author(s) -
Srivastava Suman
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201904806
Subject(s) - deep eutectic solvent , choline chloride , solvent , knoevenagel condensation , michael reaction , polyethylene glycol , eutectic system , organic chemistry , chemistry , enol , materials science , catalysis , alloy
Choline chloride and polyethylene glycol based bio‐renewable deep eutectic solvent displayed remarkable activity for the synthesis of bis‐enol scaffolds via knoevenegal condensation followed by michael addition. The green and bio‐renewable deep eutectic solvent is found to be mild, non‐toxic, bio‐compatible, with significant features such as excellent yields, facile preparation, and biodegradable with good recyclability.