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Transition‐Metal‐Free Catalyzed Dearomatizative Esterification of Indole
Author(s) -
Gao Bao,
Xu Shasha,
Du Tianri,
Li Yahui
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201904715
Subject(s) - oxindole , domino , catalysis , indole test , transition metal , chemistry , selectivity , combinatorial chemistry , halogen , organic chemistry , alkyl
3,3‐Disubstituted oxindoles are important intermediates and building blocks in organic synthesis. Herein, a domino procedure for the synthesis of various 3,3‐disubstituted oxindole from indoles has been developed. Without transition metal catalyst, indoles were selectivity dearomatized in an efficient manner without any halogen additives.