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Synthesis of Highly Substituted Fluoro Chromenones in a “ One‐Pot Four‐ Component Strategy ” Using NFSI as a Fluorinating Reagent
Author(s) -
Srikanth Reddy Narra,
Krishna Swaroop Desireddy,
Ravi Kumar Nagiri,
Sreenivas Avula,
Narsaiah Banda
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201904090
Subject(s) - acetanilide , reagent , chemistry , aryl , yield (engineering) , component (thermodynamics) , combinatorial chemistry , organic chemistry , materials science , alkyl , metallurgy , physics , thermodynamics
An efficient one pot four component strategy has been developed for the synthesis of highly substituted fluoro chromenone derivatives ( 5 a‐p ) in good yields from β ‐aryl thio acetanilide, aldehydes, cyclic 1,3‐diketones and NFSI ( N ‐Fluorobenzenesulfonimide) in presence of water. The fluoro imino chromenone intermediate 6 is isolated under the inert condition in high yield.