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One‐Pot Synthesis of N ‐Substituted Enaminones from Ketones, Aromatic Nitriles and Halides
Author(s) -
Duan Xiyan,
Yang Shijie,
Yao Changyang,
Jia Fenglin,
Wang Lin,
Li Weinan,
Meng Zhen,
Zhou Yingying,
Li Xiaoqing
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903695
Subject(s) - halide , chemistry , catalysis , aldol reaction , organic chemistry , combinatorial chemistry
A simple and convenient one‐pot copper‐catalyzed synthesis of N ‐substituted enaminones has been demonstrated from ketones, aromatic nitriles and halides. This transformation involves the aldol‐type reaction and Ullmann‐type cross coupling, which features high efficient and inexpensive Cu‐catalyst with broader diversification scope.