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Ru‐Catalyzed O‐H Insertion of Sulfoxonium Ylide and Carboxylic Acid to Synthesize α‐Acyloxy Ketones
Author(s) -
Mu Yangxiu,
Chen Yongxin,
Gao Yuanyu,
Sun Jian,
Iqbal Zafar,
Wan Yaya,
Yang Minghua,
Yang Zhixiang,
Tang Dong
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903657
Subject(s) - ylide , chemistry , catalysis , carboxylic acid , ligand (biochemistry) , selectivity , ketone , combinatorial chemistry , organic chemistry , medicinal chemistry , receptor , biochemistry
A Ru‐catalyzed method is developed for the synthesis of α‐acyloxy ketones from sulfoxonium ylide and carboxylic acid. The strategy achieves an excellent selectivity in the presence of 1,10‐phenanthroline as ligand to afford the corresponding product in good yields under simple conditions. The reaction is believed to provide an alternative method to generate ester compounds.