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Introduction of a Novel Brønsted Acidic Ionic Liquid Incorporated in UiO‐66 Nanocages for the Efficient Synthesis of Pyrimido[4,5‐d]Pyrimidines
Author(s) -
MirhosseiniEshkevari Boshra,
Ghasemzadeh Mohammad Ali,
Esnaashari Manzarbanoo,
Ganjali Saeed Taghvaei
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903642
Subject(s) - ionic liquid , nanocages , catalysis , thermogravimetric analysis , thiourea , chemistry , fourier transform infrared spectroscopy , nuclear chemistry , inorganic chemistry , organic chemistry , chemical engineering , engineering
An efficient, environmentally friendly and convenient route is described for the synthesis of pyrimido[4,5‐d]pyrimidines by using TEDA‐BAIL@UiO‐66 as a novel catalyst. In this procedure, a series of pyrimido[4,5‐d]pyrimidine derivatives were synthesized via the three‐component reactions of 6‐aminouracils, substituted aromatic aldehydes and urea or thiourea in the presence of triethylenediamine Brønsted acidic ionic liquid supported in Zr metal‐organic framework (TEDA‐BAIL@UiO‐66) as a novel catalyst under ultrasound irradiation. Excellent yields and no tedious separation procedures are the key advantages of the present method, which produced the desired products in high yields and short reaction times. Also, the catalyst was fully characterized by energy‐dispersive X‐ray spectroscopy (EDX), field emission scanning electron microscopy (FE‐SEM), Fourier transform infrared spectrophotometry (FT‐IR), X‐ray diffraction (XRD), Brunauer‐Emmett‐Teller (BET) and thermogravimetric analysis (TGA) analysis.