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General Synthesis of 3,4‐Dinitrophenyl α‐Glycopyranosides
Author(s) -
Wallace Michael D.,
Stubbs Keith A.
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903489
Subject(s) - dinitrophenyl , chemistry , glycoside , sugar , nucleophilic aromatic substitution , nucleophilic substitution , organic chemistry , stereochemistry , combinatorial chemistry , biology , antibody , immunology
A generalised simple method for the synthesis of 3,4‐dinitrophenyl α‐glycosides is described. The nucleophilic aromatic substitution of 1‐fluoro‐3,4‐dinitrobenzene can be achieved with a suite of partially protected sugar hemiacetals, under basic conditions.