Premium
Aerobic Oxidation of Thiols and In Situ Generated Thiols to Symmetrical Disulfides (Disulfanes) Catalyzed by Na 2 S 4 O 6
Author(s) -
Abbasi Mohammad,
Nowrouzi Najmeh,
Mousavi Saadat
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903099
Subject(s) - catalysis , ethylene glycol , thiourea , halide , chemistry , in situ , alkyl , thiol , peg ratio , inorganic chemistry , organic chemistry , finance , economics
A simple and efficient procedure for aerobic oxidation of thiols into symmetric disulfides using Na 2 S 4 O 6 as catalyst in situ generated by reacting Na 2 S 2 O 3 with I 2 in poly ethylene glycol (PEG‐200) has been introduced. Using this catalyst system, convenient protocol for one‐pot achievement of symmetric disulfides via aerobic oxidation of thiols in situ generated by reacting alkyl halides with thiourea is introduced.