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Iodine‐Mediated Nucleophilic Direct Oxidative α‐Acetoxylation and α‐Alkoxylation of Ketones
Author(s) -
Pogaku Naresh,
Krishna Palakodety Radha,
Prapurna Y. Lakshmi
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201903028
Subject(s) - iodine , nucleophile , simplicity , chemistry , combinatorial chemistry , oxidative phosphorylation , surface modification , reaction conditions , organic chemistry , catalysis , biochemistry , physics , quantum mechanics
Abstract A general and facile approach for the direct α‐functionalization of ketones mediated by iodine is developed. The operational simplicity, easily available starting materials, mild reaction conditions and tolerance of wide range of functional groups are the major benefits of the reaction.