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Synthesis and Characterization of Host Guest Inclusion Complexation of Cyclic Oligosaccharide with Industrially Potent Dye in Different Phases by Physicochemical Contrivance
Author(s) -
Yasmin Ananya,
Barman Biraj Kumar,
Roy Niloy,
Roy Mahendra Nath
Publication year - 2020
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201902998
Subject(s) - chemistry , cyclodextrin , spectroscopy , proton nmr , molecule , stoichiometry , fluorescence spectroscopy , inclusion compound , oligosaccharide , fluorescence , nuclear magnetic resonance spectroscopy , analytical chemistry (journal) , binding constant , two dimensional nuclear magnetic resonance spectroscopy , ultraviolet visible spectroscopy , crystallography , stereochemistry , organic chemistry , binding site , biochemistry , physics , quantum mechanics
The inclusion phenomena of β‐Cyclodextrin and Alizarin complexone was investigated by 1H NMR, 2D ROESY, UV‐Visible Spectroscopy, Fluorescence Spectroscopy, HRMS and SEM study. The change in chemical shift values in 1H NMR study established the possibility of interactions between the corresponding protons of β‐ Cyclodextrin and AC molecule, which was further confirmed by the appearance of cross peaks in 2D ROESY spectrum. The Job plot method gave the host‐guest stoitiometric ratio to be 1 : 1. The association constant and thermodynamic parameters like ΔH 0 , ΔS 0 and ΔG 0 were calculated from UV‐Visible spectroscopy. The experimental results showed, the fluorescence intensity of AC enhanced with increasing concentration of β‐ Cyclodextrin. The plot of 1/(F‐F 0 ) against 1/[β‐ Cyclodextrin] gave a straight line indicating 1 : 1 stoichiometric ratio of the inclusion complex formed. In this inclusion process, the ΔG<0 value describes the process to be a spontaneous one.