Two‐Step Preparation of Diverse 3‐Amidofurans from Chitin | Zendy

Pham Thuy Trang | Zendy; Lindsay Ashley C. | Zendy; Kim ShiWei | Zendy; Persello Laly | Zendy; Chen Xi | Zendy; Yan Ning | Zendy; Sperry Jonathan | Zendy

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Two‐Step Preparation of Diverse 3‐Amidofurans from Chitin

Author(s) -

Pham Thuy Trang,

Lindsay Ashley C.,

Kim ShiWei,

Persello Laly,

Chen Xi,

Yan Ning,

Sperry Jonathan

Publication year - 2019

Publication title -

chemistryselect

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.437

H-Index - 34

ISSN - 2365-6549

DOI - 10.1002/slct.201902765

Subject(s) - chitin , substituent , furan , chemical space , combinatorial chemistry , chemistry , nanotechnology , organic chemistry , materials science , chitosan , biochemistry , drug discovery

The synthesis of 3‐amidofurans is laborious due to the difficulty installing a nitrogen substituent at the C3 position of the furan heterocycle. 3‐Acetamido‐5‐acetylfuran (3A5AF), readily available from chitin, is a versatile biorenewable platform that can be converted into a range of functionally rich 3‐amidofurans, streamlining access to this underexplored heteroaromatic chemical space.

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