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Copper‐Catalyzed Intramolecular N ‐Arylation of Dihalobenzene and Amine‐Trichloroacetonitrile Adduct under Ultrasound‐Irradiation
Author(s) -
Nematpour Manijeh,
Fasihi Dastjerdi Hossein,
Mahboubi Rabbani Sayyed Mohammad Ismaeil,
Tabatabai Sayyed Abbas
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201902411
Subject(s) - adduct , chemistry , catalysis , imidazole , amine gas treating , intramolecular force , benzene , copper , medicinal chemistry , organic chemistry , photochemistry , polymer chemistry
A novel series of 2‐(trichloromethyl)‐1 H ‐ benzo[ d ]imidazole analogs were synthesized via an ultrasonic‐assisted, one‐pot, copper‐catalyzed three‐component reaction of the amine‐trichloroacetonitrile adduct and 1, 2‐dihalo benzene at room temperature. Affordable starting materials, simple work‐up method, short reaction time process and relatively high yields were the advantages of this modified version of Ullmann reaction.