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Synthesis of Various N ‐heterocycles Using the Ugi Four‐Center Three‐Component Reaction
Author(s) -
Mohammadkhani Leyla,
Heravi Majid M
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201902029
Subject(s) - bifunctional , component (thermodynamics) , ugi reaction , chemistry , center (category theory) , combinatorial chemistry , isocyanide , stereochemistry , organic chemistry , crystallography , physics , catalysis , thermodynamics
Ugi four‐center three‐component reaction (U‐4 C‐3CR) as actually an important development of the well‐known Ugi four‐component reaction (U‐4CR). In U‐4 C‐3CR, one of the components is bifunctional, reducing the components of U‐4CR to three components. This review aims to provide the application of U‐4 C‐3CR in the synthesis of different N ‐heterocyclic compounds with four‐, five‐, six‐, and seven‐membered rings as well as fused heterocycles.