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Electrochemical Sensing of Anesthetics using Polythiophene Coated Glassy Carbon Electrodes
Author(s) -
Ramkumar Ramya,
Sangaranarayanan M. V.
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901982
Subject(s) - cyclic voltammetry , differential pulse voltammetry , polythiophene , materials science , electrode , fourier transform infrared spectroscopy , glassy carbon , polymerization , detection limit , electrochemistry , electrochemical gas sensor , conductive polymer , analytical chemistry (journal) , polymer , chemistry , chemical engineering , organic chemistry , chromatography , composite material , engineering
A novel electrochemical sensor for anesthetics employing the polymerization of Thiophene onto glassy carbon electrodes is demonstrated. The polymer was characterized by electrochemical and morphological characterizations using cyclic voltammetry, differential pulse voltammetry, Fourier transform infrared spectroscopy and scanning electron microscopy. This polythiophene modified electrode was employed for sensing anesthetics and a lowest detection limit of 35 nM, 50 nM and 20 nM were obtained for Procaine, Benzocaine and Procainamide respectively. The interference studies showed the selectivity of this electrode in the presence of common interfering agents. The Dopaminergic effect of Procaine is studied by varying concentrations of dopamine and a thorough study established the profound effect.