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Acid‐treated Graphitic Carbon Nitride Nanosheets as Fluorescence Probe for Detection of Hemin
Author(s) -
Guo Zhaoliang,
Li Bingdong,
Zhang Yuqian,
Zhao Qiannan,
Zhao Jian,
Li Lijuan,
Feng Liwei,
Wang Manman,
Meng Xianguang,
Zuo Guifu
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901841
Subject(s) - hemin , fluorescence , detection limit , graphitic carbon nitride , quenching (fluorescence) , chemistry , nuclear chemistry , materials science , photochemistry , analytical chemistry (journal) , chromatography , photocatalysis , biochemistry , optics , heme , physics , enzyme , catalysis
An acid‐treated, oxidized graphitic carbon nitride nanosheets (g‐C 3 N 4 NSs) was successfully synthesized and applied as a fluorescence probe for the detection of hemin based on the inner filter effect (IFE). The results indicated that the fluorescence quenching of g‐C 3 N 4 NSs caused by hemin was attributed to the overlap between absorption spectrum of hemin and emission spectrum of g‐C 3 N 4 NSs. It is confirmed that the g‐C 3 N 4 NSs exhibited a highly sensitive and selective for detection of hemin. Under the optical condition, the fluorescence changing of g‐C 3 N 4 NSs is related to the concentration of hemin ranging from 0.5 – 25 μM with a detection limit of 0.15 μM. Moreover, the fluorescence probe has been successfully applied to detect hemin in human blood. Overall, a novel and efficient fluorescence‐based method was developed supported by g‐C 3 N 4 NSs, which is a promising material for application in sensing and cell imaging.
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