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A New and Eco‐Friendly Method for Reduction of Ketones in Water
Author(s) -
Türkmen Gülşah,
Kavukcu Serdar Batıkan
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901662
Subject(s) - piperidine , chemistry , catalysis , hydroxymethyl , ruthenium , environmentally friendly , rhodium , bifunctional , yield (engineering) , iridium , organic chemistry , medicinal chemistry , combinatorial chemistry , materials science , ecology , metallurgy , biology
This paper reports a new, practical, and environmentally friendly catalytic system for reduction of the ketones to the related alcohols with efficient reaction performance in water. Catalysts were generated in situ from rhodium, ruthenium and iridium transition metal compounds with commercially available piperidines [Piperidine ( L 1 ), 2‐hydroxymethylpiperidine ( L 2 ), 3‐hydroxymethylpiperidine ( L 3 ), 4‐hydroxymethylpiperidine ( L 4 ), 4‐hydroxypiperidine ( L 5 )] as bifunctional ligands. Catalyst generated from RuCl 2 (PPh 3 ) 3 and 4‐hydroxymethyl piperidine have shown the best activity in aqueous media which gave a 100% product yield. RuCl 2 (PPh 3 ) 3 , has showed a better efficiency than [RuCl 2 ( p ‐cymene)] 2 , IrCl(PPh 3 ) 3 , or RhCl(PPh 3 ) 3 in HCOOH–HCOONa buffer solution. This study was also investigated the relationship between the structure of hydroxymethyl piperidine ligands and the catalytic activity.