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Metal‐Free One‐Pot Conversion of Olefins and Alkynes to Amides Using TsNBr 2 , I 2 and Aqueous NH 3 at Room Temperature
Author(s) -
Loukrakpam Dineshwori Chanu,
Phukan Prodeep
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901530
Subject(s) - phenylacetylene , amide , aqueous solution , styrene , yield (engineering) , chemistry , iodine , primary (astronomy) , alkali metal , metal , polymer chemistry , inorganic chemistry , organic chemistry , materials science , catalysis , copolymer , polymer , physics , astronomy , metallurgy
A new synthetic procedure has been developed for the synthesis of primary aromatic amide from different types of styrene and phenylacetylene using TsNBr 2 , I 2 –aqueous NH 3 solution at room temperature. The reaction proceeds via the formation of α‐bromoketone & α,α‐dibromoketone as intermediate from styrene and phenylacetylene respectively in the presence of TsNBr 2 at the initial stage of the reaction. Subsequent treatement of the reaction mixturewith molecular iodine and aq. NH 3 (25%) produces the corresponding amide. Various primary aromatic amides were obtained in appriciable yield at room temperature.