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Phase Transfer Catalyst Assisted One‐Pot Synthesis of 5‐(Chloromethyl)furfural from Biomass‐Derived Carbohydrates in a Biphasic Batch Reactor
Author(s) -
Onkarappa Sharath Bandibairanahalli,
Dutta Saikat
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901347
Subject(s) - furfural , levulinic acid , yield (engineering) , chemistry , solvent , catalysis , biomass (ecology) , organic chemistry , batch reactor , phase transfer catalyst , nuclear chemistry , materials science , agronomy , metallurgy , biology
Abstract 5‐(Chloromethyl)furfural (CMF), a bio‐renewable chemical building block, has been produced in good isolated yields from biomass‐derived carbohydrates within a closed aqueous HCl‐1,2‐dichloroethane biphasic reactor in the presence of benzyltributylammonium chloride (BTBAC) as a phase transfer catalyst (PTC). The solvent‐economic, one‐pot strategy afforded CMF in 73% isolated yield (90 °C, 3 h) from sucrose with a combined yield of 84% for CMF and levulinic acid. The process was optimized on temperature, duration, solvent, type, and loading of PTC. Use of BTBAC led to nearly 10% increase in yield of CMF for all substrates when compared to control reactions.