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Fe 3 O 4 @SiO 2 /EP.EN.EG.Cu as a Highly Efficient and Recoverable Catalytic System for Synthesis of 1,4‐Disubstituted 1,2,3‐Triazole Derivatives via the Click Reaction
Author(s) -
Ebadi Amin,
Rajabzadeh Maryam,
Khalifeh Reza
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901237
Subject(s) - catalysis , halide , alkyl , reaction conditions , chemistry , click chemistry , combinatorial chemistry , materials science , medicinal chemistry , organic chemistry
A magnetic nanostructured core–shell Fe 3 O 4 @SiO 2 /EP.EN.EG.Cu has used as an efficient heterogeneous catalyst for the synthesis of 1,4‐disubstituted 1,2,3‐triazole derivatives through click reaction, under mild reaction conditions. A variety of epoxides, alkyl or benzyl halides was used to afford the corresponding 1,4‐disubstituted 1,2,3‐triazoles. The catalyst could be easily separated by using an external magnet from the reaction mixture and reused seven times without significant loss of catalytic activity.