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Nickel‐Catalyzed Heck Reaction of Aryl Halides and Terminal Olefins Using Zinc/Triflate Ligand/DMA/TBAB
Author(s) -
Mishra Satyendra,
Halpani Chandni G,
Patel Sejal
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901131
Subject(s) - aryl , chemistry , catalysis , heck reaction , zinc , trifluoromethanesulfonate , halide , methyl acrylate , nickel , polymer chemistry , bromide , styrene , coupling reaction , organic chemistry , palladium , copolymer , alkyl , polymer
A straightforward and proficient procedure for the nickel‐catalyzed Heck C−C coupling reaction of different aryl halides and with olefins has been accomplished. The reaction, was catalyzed via combination of NiBr2(PPh3)2, zinc powder, additive (BMIM.OTf), K3PO4 as a base in the presence of solvents N,N‐dimethylacetamide (DMA) and Tetra‐n‐butylammonium bromide(TBAB). The arylation of methyl acrylate and styrene with various aryl iodides under optimized catalytic systems, showed excellent yield of the products. Remarkably, base (K3PO4), additive (BMIM.OTf) and the solvent (TBAB/DMA) have shown an indispensable effects on the efficacy of the reaction and it has been found to be in most favorable condition for heck reaction.