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An Account on the Versatility of Dopamine as a Functional Monomer in Molecular Imprinting
Author(s) -
Zaidi Shabi Abbas
Publication year - 2019
Publication title -
chemistryselect
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 34
ISSN - 2365-6549
DOI - 10.1002/slct.201901029
Subject(s) - imprinting (psychology) , dopamine , monomer , molecular imprinting , polymerization , chemistry , nanotechnology , combinatorial chemistry , polymer , materials science , biochemistry , organic chemistry , biology , catalysis , neuroscience , selectivity , gene
Abstract Apart from being a vital catecholamine molecule responsible for the proper functioning of central nervous system (CNS), hormonal and renal systems, dopamine (DA) has also been increasingly employed as a functional monomer in the fabrication of surface molecular imprinting of valuable analytes, especially for proteins. The application of dopamine as functional monomer was inspired from mussel adhesion protein, its capability of self‐polymerization under weak alkaline aqueous solution resulting into thin biocompatible highly cross‐linked polydopmaine (PDA) film and cost‐effectiveness. Furthermore, it could adhere strongly on various (organic and inorganic) substrates without any attachment, and possesses plenty of noncovalent functionalities such as amino‐containing groups, hydroxyl‐containing groups and π‐π for further modifications. In this first ever review, we focused our attention on the utilization and influence of DA as a functional monomer in the fabrication of molecular imprinting and discussed it comprehensively.